An otherwise healthy 57-year-old woman presents for further evaluation following an incidental laboratory result discovered on her yearly employment health evaluation.
Familial hypercholesterolemia (FH) is the most common inherited metabolic disease caused by mutations of the genes involved in low-density lipoprotein cholesterol (LDL-C) metabolism.
A patient’s response to warfarin is affected by several factors such as the use of other drugs, disease states, age, dietary vitamin K, and genetic poymorphisms.